July 2018
Dear Researcher,
We are pleased to present the e-Lynx, a newsletter devoted to keeping our customers up-to-date on new technologies, our new products, suppliers, activities and promotions.
- Promotions
- New Products
- New Literature
- Technical Reports
- New Videos
- MJSBioLynx Well Being
PROMOTIONS
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Vector Laboratories - 2 Special Offers for IHC and IF
VectaSALE !
Save 20% OFF Vector Laboratories' "Vecta" Products for Immunohistochemistry and Immunofluorescence.
- VECTABOND® Reagent Tissue Section Adhesive
- VECTASTAIN® Avidin-Biotin (ABC) Based Detection
- VectaFluor™ Ready-to-Use DyLight® Dye-conjugated Antibody Reagents
- VECTASHIELD® Antifade Mounting Media
- VectaMount® Permanent Mounting Medium
- VectaCell™ Products for Live Cell Imaging
PLUS...
Get a FREE Package of ImmEdge™ Hydrophobic Barrier PAP Pens or ImmPrint™ Histology Pens when You Order $1000 or More of Any Vector Laboratories Products.
Click here for more information.
Click here to order or request a quote.
Offers valid until August 31st, 2018
VectaSale: Promo Code VECTA2018. Cannot be combined with other discounts.
Free Pen Offer: Promo Code VECTPEN18. Customer must order $1000 of Vector products, before taxes, on a single order.
USA Scientific - Buy 3, Get 1 FREE on TipOne® Pipette Tips
- Excellent Quality at an Affordable Price
- Secure, low force fit and accurate delivery
- No clarifiers or processing additives
- Certified free of detectable RNase, DNase, DNA, and pyrogens
- Refillable system saves storage, reduces waste, and is easy to load
For a limited time, Buy any 3 packs of TipOne® Pipette Tips and Get 1 Pack FREE!
Click here for more information.
Click here to order or request a quote.
Offer valid until August 31st, 2018.
Cannot be combined with other offers or discounts.
Free item must be of equal or lesser value. All items must be on the same order.
Promotion Code US0618.
NEW PRODUCTS
Micronic – Screw Cap Ultra for Tubes with Internal Thread
The O-ring of the cap falls within the tube, creating a "hard" stop. This design enhances automated and manual handling (closure does not depend on the closing force of the cap but on fixed pressure) while also optimizing sealing performance.
- Compatible with the Micronic Screw Cap Recappers and other automated systems
- Available in 4 different premium ''pearl'' colours: blue, yellow, light green and red
- Ideal for sample storage at ultra-low temperatures or for sample transportation
- High-quality silicon O-ring
- Resists chemical solvents
- Certified class 7 clean room production
- RNase/DNase and Pyrogen free
Click here to order or request a quote.
Platypus Technologies – Silver Coated Substrates
- Silver coated silicon wafers, microscope slides and coverslips
- Fabrication in cleanroom environment
- Electron beam deposition for thigh control of film thickness
- 99.99% pure silver
- Optional titanium adhesion layer
- Custom silver coated products are available
Applications include:
- Surface Plasmon Resonance (SPR)
- Self-Assembled Monolayers (SAMs)
- High Reflectivity Mirrors
- Atomic Force Microscopy
- Electrochemistry
- High Performance Printed Electrodes
- Sensor and Biosensors
Click here to order or request a quote.
G-Biosciences – Wild Type Purified Membrane Proteins
Wild type purified membrane proteins are isolated by patented technology that allows for the isolation in solution of full length and pure to highly pure membrane proteins. These include GPCRs, ion channels, transporters, receptors and viral proteins. These purified membrane proteins retain their structural and functional integrity and purification does not utilize refolding steps or mutagenesis.
Click here to order or request a quote.
NEW LITERATURE
Heathrow Scientific - 2018 Lab Supplies and Equipment Catalogue
This catalogue features Heathrow’s line of functional racks and storage solutions, small instruments, and many more lab essentials.
Click here to download.
Contact our Customer Service Team to request printed copies of this publication, e-mail sales@biolynx.ca or call 1-888-593-5969.
TECHNICAL REPORTS
Associates of Cape Cod Inc. – 1→3-ß-D-Glucan: Pharmaceutical Contaminant and Biological Response Modifier
American Pharmaceutical Review™ article re-publication.
The establishment of consistent safety and efficacy of parenteral pharmaceutical products is a key goal in GMP operations. Within the spectrum of activities that support GMP operations, the control of bioactive contaminants is a critical concern. Practically, and perhaps principally, this has meant sterility and within-specification endotoxin burdens. Over the last seven decades, tests for bacterial endotoxin burdens have developed from exclusively animal-based bio-assays to LAL (Limulus Amebocyte Lysate), or LAL-derivative, biochemical assays and mammalian cell-based assays. These methods have been enshrined in national and international regulatory requirements and have performed extremely well in maintaining a high level of endotoxin-related safety in modern parenterals. This success has not engendered complacency, however, and pharmaceutical science relating to bioactive contaminants has moved forward to identify other bioactive materials whose uncontrolled presence in parenterals can potentiate risk to safety and efficacy. One such commonly encountered bioactive is 1→3-β-D-Glucan.
Click here to read more.
EpiCypher – Anatomy of a Recombinant Nucleosome
Nucleosome substrates are emerging tools for the in vitro study of chromatin and epigenetic regulation, with applications from basic research to high-throughput drug screening. The advent of recombinant designer nucleosomes (dNucs) carrying fully defined covalent modifications of the histone proteins (e.g. lysine acylation) or wrapping DNA (e.g. 5’ methylcytosine) enables novel or dramatically improved approaches (e.g. reader binding, enzymatic assays, antibody profiling) for next-generation chromatin research. This document proposes the minimal thresholds for the assembly and quality validation of these reagents; essential if they are to yield reproducible, biologically-relevant data.
Click here to read more.
Hycult Biotech - Neutrophil Elastase in Ocular Graft-Versus-Host Disease
The purpose of this study was to compare neutrophil elastase levels in tears of oGvHD patients with normal subjects. 14 oGvHD patients and 14 matched normal controls were enrolled in the study. Neutrophil elastase (Product HYBHK319) was measured from tear washes of both eyes. The results demonstrated that NE-levels of oGvHD patients were 250-fold higher in comparison to the matched controls. Secondary markers such as MPO, MMP-8 and MMP-9 were also significantly elevated in the oGvHD group. This study shows that NE can be a potential marker of ocular inflammation. However, the effectiveness of NE as an inflammatory biomarker remain unknown. Large, well-designed prospective studies are needed to test the effectiveness of an NE assay.
Click here to read more. (Link to Hycult Biotech website)
Cygnus Technologies – Bioprocess Impurity Testing FAQs
Get answers to questions such as: What are the allowable limits of HCP detection? What is the "High Dose Hook Effect"? Which antibodies to use for CHO 3G? What is matrix interference? How to evaluate samples for dilutional linearity?
Click here to read more. (Link to Cygnus Technologies website)
NEW VIDEOS
Micronic - Screw Cap Recapper CS500
The handheld device offers users the ability to cap, decap or recap a row of 8 tubes in less than 5 seconds - 10 times faster than by hand! It helps minimize sample evaporation and significantly improves productivity. In addition, the Screw Cap Recapper ensures each screw cap is tightened securely and uniformly.
Click here to watch. (Link to YouTube)
NuGEN – Recorded Webinar: Mining the Post-Mortem Human Brain for Neurodegenerative Markers
Dr. Steve Sheardown, Head of Molecular Biology and Cell Engineering at pharmaceutical company Cerevance, discusses a technology platform called NETSseq (Nuclear Enriched Transcript Sort sequencing). Cerevance uses NETSseq to interrogate the molecular diversity of individual neuronal cell types in human tissue to understand their genetic complexity, the contribution that each of these makes to circuit function, and, in the context of brain disorders, their potential for therapeutic intervention.
Click here to watch. (Link to NuGEN website)
Mirus Bio - The Simplicity of Virus-Mediated Gene Delivery
Difficult to transfect cell types, non-dividing cells and the need for stable cell line generation are some reasons why researchers may turn to virus mediated gene delivery.
Click here to watch. (Link to YouTube)
MJSBioLynx WELL BEING
Anxious Teens 'Tune in to Present Moment' to Overcome Mental Illness
"The B.C. Children's Hospital program helps struggling youth practice meditation and mindfulness to help improve their mental health. Pediatrician Dr. Dzung Vo co-directs the program. "I'm trying to teach young people how to be just fully present in the moment on purpose and without judgment or with a sense of self compassion and acceptance," Vo said."
Click here to read more. (Link to CBC website)
Click here to visit the MJSBioLynx Well Being website.