MPO, Rat, Monoclonal Antibody 2D4
- Supplier: Hycult Biotech
Product Description
- The monoclonal antibody 2D4 reacts with rat myeloperoxidase (MPO). MPO is a glycoprotein with an alpha2beta2 heteromultimer expressed in all cells of the myeloid linage. MPO is abundantly present in azurophilic granules of polymorphonuclear neutrophils. It is an important enzyme used during phagocytic lysis of engulfed foreign particles which takes part in the defense of the organism through production of hypochlorous acid (HOCl), a potent oxidant. MPO is rapidly released by activated polymorphonuclear neutrophils. Involvement of MPO has been described in numerous diseases such as atherosclerosis, lung cancer, Alzheimer's disease and multiple sclerosis. Autoimmune antibodies to MPO are involved in Wegeners disease. Since the discovery of MPO deficiency, initially regarded as rare and restricted to patients suffering from severe infections, MPO has more attracted clinical attention. In experimental studies antibodies to MPO can be used for various purposes ranging from flow cytometric analysis to detection of polymorphonuclear neutrophils in tissue sections. The monoclonal antibody 2D4 cross reacts with mouse MPO.
- Applications: Frozen sections, Flow Cytometry , Immunoassays , Immunofluorescence
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Product Options
| Product Number | Description | Package Size | List Price (CAD) | ||
|---|---|---|---|---|---|
| HYBHM303020UG | MPO, Rat, mAb 2D4, 20 µg | 20 µg |
CA$235.00
|
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| HYBHM3030100UG | MPO, Rat, mAb 2D4, 100 µg | 100 µg |
CA$880.00
|
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| HYBHM3030500UG | MPO, Rat, mAb 2D4, 500 µg | 500 µg |
CA$1,850.00
|
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